Indianapolis at  Baltimore 4:30 pm

It will be strength vs. strength as the Colts will bring the third-ranked offense to Baltimore to face the Ravens' top-ranked defense. Coming off a 23-8 win over the Chiefs in a wild-card game, the Colts are in the divisional playoffs for a fourth straight year. The Ravens, winners of the AFC North, are in the playoffs for the first time since 2003 and enjoyed a bye week as the AFC's No. 2 seed. The teams last met in the opening game of 2005 with Indianapolis winning 24-7 in Baltimore, where the Colts made their home until 1984. In 2003, Colts quarterback Peyton Manning and Ravens QB Steve McNair (then of the Titans) were the league's co-MVPs.

Indianapolis Record 13-4
Baltimore Record 13-3
PICK TO WIN: Indianapolis Colts 27-17

Eagles at Saints 8:00 pm
As winners of the NFC East in five of the past six season, the Eagles are no strangers to the playoffs. No so for the Saints, who are in the postseason for the first time since 2000. Even their head coach is a rookie, but Sean Payton has been largely credited for the Saints' turnaround from a 3-13 record in 2005, earning him Coach of the Year honors. The Eagles come to New Orleans after dispatching the Giants in the wild-card round with a last-second David Akers kick. Philly was the victim of a game-winning kick when the Saints knocked off the Eagles in Week 6.