PIT(6-3) @ KC (2-7) -Arrowhead Stadium. Pittsburgh Steelers Regular Season Leaders: Passing-Ben Roethlisberger Rushing-Rashard Mendenhall Receiving-Santonio Holmes. Kansas City Chiefs Regular Season Leaders: Passing-Matt Cassel Rushing-Larry Johnson Receiving-Dwayne Bowe.
Picks: MD PIT WIN 28-10 – ED PIT WIN 45-15

SF(4-5) @ GB (5-4) -Lambeau Field. San Francisco 49ers Regular Season Leaders: Passing-Shaun Hill Rushing-Frank Gore Receiving-Vernon Davis Green Bay Packers Regular Season Leaders: Passing-Aaron Rodgers Rushing-Ryan Grant Receiving-Donald Driver.
Picks: MD GB WIN 21-14 – ED GB WIN 35 -14

CLE (1-8) @ DET (1-8) -Ford Field. Cleveland Browns Regular Season Leaders: Passing-Derek Anderson Rushing-Jamal Lewis Receiving-Mohamed Massaquoi. Detroit Lions Regular Season Leaders: Passing-Matthew Stafford Rushing-Kevin Smith Receiving-Calvin Johnson.
Picks: MD CLE WIN 10-3 – ED CLE WIN 21 -7

IND (9-0) @ BAL (5-4) -M&T Bank Stadium. Indianapolis Colts Regular Season Leaders: Passing-Peyton Manning Rushing-Joseph Addai Receiving-Reggie Wayne. Baltimore Ravens Regular Season Leaders: Passing-Joe Flacco Rushing-Ray Rice Receiving-Derrick Mason.
Picks: MD IND WIN 28-14 – ED IND WIN 31 -24

SEA (3-6) @ MIN (8-1) -Mall of America Field. Seattle Seahawks Regular Season Leaders: Passing-Matt Hasselbeck Rushing-Julius Jones Receiving-T.J. Houshmandzadeh. Minnesota Vikings Regular Season Leaders: Passing-Brett Favre Rushing-Adrian Peterson Receiving-Sidney Rice.
Picks: MD MIN WIN 34-14 – ED MIN WIN 31 -7

WAS (3-6) @ DAL (6-3) -Cowboys Stadium. Washington Redskins Regular Season Leaders: Passing-Jason Campbell Rushing-Clinton Portis Receiving-Santana Moss. Dallas Cowboys Regular Season Leaders: Passing-Tony Romo Rushing-Marion Barber Receiving-Miles Austin.
Picks: MD DALWIN 24-14 – ED DAL WIN 28 -14

BUF (3-6) @ JAC (5-4) -Jacksonville Municipal Stadium. Buffalo Bills Regular Season Leaders: Passing-Trent Edwards Rushing-Fred Jackson Receiving-Lee Evans. Jacksonville Jaguars Regular Season Leaders: Passing-David Garrard Rushing-Maurice Jones-Drew Receiving-Mike Sims-Walker.
Picks: MD JAC WIN 14-10- ED JAC WIN 21 -7

ATL (5-4) @ (5-4) NYG -Giants Stadium. Atlanta Falcons Regular Season Leaders: Passing-Matt Ryan Rushing-Michael Turner Receiving-Roddy White. New York Giants Regular Season Leaders: Passing-Eli Manning Rushing-Brandon Jacobs Receiving-Steve Smith.
Picks: MD NYG WIN 17-14 – ED NYG WIN 21 -14

NO (9-0) @ TB (1-8) -Raymond James Stadium. New Orleans Saints Regular Season Leaders: Passing-Drew Brees Rushing-Pierre Thomas Receiving-Marques Colston.Tampa Bay Buccaneers Regular Season Leaders: Passing-Josh Johnson Rushing-Cadillac Williams Receiving-Kellen Winslow.
Picks: MD NO WIN 38-21 – ED NO WIN 48 -7

ARI (6-3) @ STL (1-8) -Edward Jones Dome. Arizona Cardinals Regular Season Leaders: Passing-Kurt Warner Rushing-Beanie Wells Receiving-Larry Fitzgerald. St. Louis Rams Regular Season Leaders: Passing-Marc Bulger Rushing-Steven Jackson Receiving-Donnie Avery.
Picks: MD ARI WIN 24-14 – ED ARI WIN 30 -14

NYJ (4-5) @ NE (6-3) -Gillette Stadium. New York Jets Regular Season Leaders: Passing-Mark Sanchez Rushing-Thomas Jones Receiving-Jerricho Cotchery. New England Patriots Regular Season Leaders: Passing-Tom Brady Rushing-Laurence Maroney Receiving-Randy Moss.
Picks: MD NE WIN 21-9 – ED NE WIN 31 -3

CIN (7-2) @ OAK (2-7) -Oakland Coliseum. Cincinnati Bengals Regular Season Leaders: Passing-Carson Palmer Rushing-Cedric Benson Receiving-Chad Ochocinco. Oakland Raiders Regular Season Leaders: Passing-JaMarcus Russell Rushing-Michael Bush Receiving-Zach Miller.
Picks: MD Eagles WIN 17-14 – ED CIN WIN 21 -14

SD (6-3) @ DEN (6-3) -Invesco Field at Mile High. San Diego Chargers Regular Season Leaders: Passing-Philip Rivers Rushing-LaDainian Tomlinson Receiving-Vincent Jackson. Denver Broncos Regular Season Leaders: Passing-Kyle Orton Rushing-Knowshon Moreno Receiving-Brandon Marshall.
Picks: MD DEN WIN 17-10 – ED DEN WIN 21-10

PHI (5-4) @ CHI (4-5) -Soldier Field. Philadelphia Eagles Regular Season Leaders: Passing-Donovan McNabb Rushing-LeSean McCoy Receiving-DeSean Jackson. Chicago Bears Regular Season Leaders: Passing-Jay Cutler Rushing-Matt Forte Receiving-Devin Hester.
Picks: MD PHI WIN 30-21 – ED PHI WIN 35 -17